Dr. Elena Kinder and Dr. Heap work for BABYCO, the world's leading manufacturer in baby products. What the public doesn't know, however, is that Dr. Kinder and Dr. Heap are secretly working on cracking the code to "baby talk" which is actually a highly sophisticated language which allows babies to communicate the knowledge of the secrets of the universe with which they are born. Problems arise when Sly, the smartest of the babies, escapes from the lab and unites the babies of the outside world to help free the babies trapped in the lab. Kinder and Heap must find Sly before it is too late.

In this high-adventure sequel the baby geniuses find themselves at the center of a nefarious scheme led by powerful media mogul Bill Biscane. Joining the babies in their battle against evil is a legendary baby named Kahuna. Part ultra-cool spy, part superhero, Kahuna joins babies Archie, Finkleman, Alex and Rosita in a race against time to stop the villainous Biscane from using his state-of-the-art satellite system to control the minds of the world's population.